DSpace Collection: https://dspace.sduaher.ac.in/jspui/handle/123456789/769 2026-04-04T02:48:17Z 2026-04-04T02:48:17Z A prospective study to assess for the prognostic value of tumour volume reduction rate in head and neck cancer, during definitive chemo-radiation in a tertiary care hospital Santhosha. Bhaskar Vishwanathan., Vishwanathan. Geeta S N, S N https://dspace.sduaher.ac.in/jspui/handle/123456789/9578 2025-10-18T08:48:17Z 2023-06-01T00:00:00Z Title: A prospective study to assess for the prognostic value of tumour volume reduction rate in head and neck cancer, during definitive chemo-radiation in a tertiary care hospital Authors: Santhosha.; Bhaskar Vishwanathan., Vishwanathan.; Geeta S N, S N Abstract: Tumour volume (TV) is an important factor influencing Radiation therapy(RT) outcome of patients. Logically, total dose and its fractionation should be tailored to the initial number of tumor cells which strongly correlated with tumor volume (TV) rather than to the tumor diameter or stage T. Aims and objectives: To assess tumour volume reduction rate weekly in patients with biopsy proven head and neck cancers treated with definitive chemo-radiation ant to correlate with histology haemoglobin and BMI . Methods and Materials: All oral cavity, oropharyngeal, hypopharyngeal, nasopharyngeal, and laryngeal cancer patients meeting inclusion criteria were included after obtaining informed written consent. All patients received definitive chemoradiation with weekly CT scanning of head and neck for the assessment of tumour and nodal volume response to chemoradiation. Tumour volume was contoured every week on CT scanning images. Tumour volume response rate (TVRR) was calculated. Results: Fourty patients were recruited. Most tumours were MDSCC accounting for 55%. Phase 1 TVRR was marginal which steeply increase 3rd week onwards during chemoradiation. In the phase 2, TVRR increased markedly. The mean TVRR on week 7 for WDSCC, MDSCC and PDSCC were 14.38 ± 7.01%, 15.01 ± 7.95% and 19.82 ± 10.44% respectively. The maximum TVRR was observed on the 7 th week of treatment which is the last week of treatment period. Patients with PDSCC had higher TVRR . Conclusion: Our study demonstrated TVVR increased markedly third week onwards and it was found to be maximum at 7th week . 2023-06-01T00:00:00Z Quantification of Dose-Volume and Dose-Length Parameters for Cervical Esophageal Stricture in Head and Neck Irradiation with the 3DCRT and IMRT Technique. Pushpa Naga C.H., Janaki M.G., Arul Ponni T.R., Kirthi Koushik A.S., Manjunath G.N https://dspace.sduaher.ac.in/jspui/handle/123456789/6620 2020-05-23T08:26:02Z 2017-01-01T00:00:00Z Title: Quantification of Dose-Volume and Dose-Length Parameters for Cervical Esophageal Stricture in Head and Neck Irradiation with the 3DCRT and IMRT Technique. Authors: Pushpa Naga C.H., Janaki M.G., Arul Ponni T.R., Kirthi Koushik A.S., Manjunath G.N 2017-01-01T00:00:00Z Does Fall In Serum Glutathione Predict The Long-Term Outcome To Concurrent Chemoradiation For Cervical Cancer Patients? Manjunath Gudibande Narasappa, Janaki Manur Gururajachar ,Vasudha Kambam Chokkanna2 , Mohankumar Somashekar1 https://dspace.sduaher.ac.in/jspui/handle/123456789/4850 2025-03-26T11:40:54Z 2016-01-01T00:00:00Z Title: Does Fall In Serum Glutathione Predict The Long-Term Outcome To Concurrent Chemoradiation For Cervical Cancer Patients? Authors: Manjunath Gudibande Narasappa, Janaki Manur Gururajachar ,Vasudha Kambam Chokkanna2 , Mohankumar Somashekar1 2016-01-01T00:00:00Z Breast conserving surgery in early breast cancer evidence based review Gopinath K S Saishruthi Rai https://dspace.sduaher.ac.in/jspui/handle/123456789/3775 2018-06-30T10:11:38Z 2012-01-01T00:00:00Z Title: Breast conserving surgery in early breast cancer evidence based review Authors: Gopinath K S Saishruthi Rai 2012-01-01T00:00:00Z