https://dspace.sduaher.ac.in/jspui/handle/123456789/438 2026-02-08T17:41:43Z https://dspace.sduaher.ac.in/jspui/handle/123456789/9350 Title: ROLE OF SHEAR WAVE OF SEVERITY OF BENIG CORRELATION WITH INT DISSERTATIONSUBMITTEDTO SRIDEVARAJURSACADEMYOFHIGHEREDUCATIONAND RESEARCH,KOLAR,KARNATAKA Inpartialfulfilmentoftherequirementsforthedegreeof DEPT. OF RADIODIAGNOSIS DEPARTMENT OF RADIODIAGNOSIS, SRI DEVARAJ URS MEDICALCOLLEGE, i ELASTOGRAPHY IN DETERMINATION BENIGN PROSTATE HYPERPLAS INTERNATIONAL PROSTATE SCORE Authors: ANNE SURYA KANTH Abstract: Introduction: Not much studied in elastography (SWE) in patients with benign prostate hypertrophy (BPH). The purpose of this research was to evaluate the use of SWE in determining the severity of BPH and its related with the international prostate symptom score (IPSS). Methodology: This cross-sectional study was conducted at at R.L. Jalappa Hospital and Research Center attached to SDUMC, Kolar shear wave elastography in determination of sev correlation with international prostate symptom score. For this, adult patients of bladder outflow obstruction were included in the study individuals with normal prostate glan Results: Mean SWE values for patients with mild, moderate and severe IPSS scores was 25.8, 35, and 40 kPa respectively, with a significant difference between them. And we observed that SWE values correlated significantly with IP and prostate volume (r = 0.82, p value < 0.001). It was observed that mean SWE for BPH patients was 37.1 ± 5.02, which was significantly higher as compared to non (25.8 ± 3.37), p value < 0.01. Based on ROC of 94.2%, 98.10% respectively for predicting BPH Conclusion: Prostate elastography imaging using transabdominal ultrasound (US) is a non invasive method that allows for a more objective evaluation of prostat Keywords: benign prostate hypertrophy; elastography; bladder outlet obstruction; ultrasound xxii ABSTRACT India have evaluated the usefulness of shear wave rostate Department of Radio to assess the role of severity of benign prostate hyperplasia and study. In addition, age matched gland were chosen as controls. IPSS score (r = 0.84, p value < 0.001) analysis, SWE had a sensitivity and specificity prostate stiffness. Radio-Diagnosis erity with symptoms SS non-BPH subjects none 2024-07-01T00:00:00Z https://dspace.sduaher.ac.in/jspui/handle/123456789/9349 Title: SONOGRAPHIC EVALUATION OF GALLBLADDER MORPHOLOGY AND MOTILITY IN TYPE 2 DIABETES MELLITUS – A CASE CONTROL OBSERVATIONAL STUDY Authors: SIVA SIDHANTH, Y. Abstract: Introduction: Diabetes mellitus is a prevalent endocrine disorder that is currently increasing in prevalence due to the progress of modern lifestyles. The purpose of this research was to sonographically compare the gall bladder morphology and motility between diabetic and nondiabetic patients. Aim:  To assess the gallbladder volume (fasting & postprandial) and wall thickness in patients with Type II Diabetes mellitus.  To evaluate motility & morphological factors between diabetic and nondiabetic individuals.  To determine association of gallbladder volumes and contractility index with duration of diabetes. Methodology: This case control observational study was conducted at Department of Radiodiagnosis, R.L.Jalappa Hospital and Research Centre, attached to Sri Devaraj Urs Medical College, to sonographically compare the gall bladder morphology and motility between diabetic and non-diabetic patients. For this, type 2 DM cases and non-diabetic controls were included in the study. All patients underwent ultrasound examination of gall bladder to assess their morphology and motility. Results: Mean fasting gall bladder volume was significantly larger in DM patients as compared to non-DM subjects (36.75 ± 11.93 vs 30.80 ± 7.18 ml, p value < 0.01). Similarly, mean post-prandial gall bladder volume was significantly larger in DM patients as compared to non-DM subjects (23.27 ± 8.93 vs 18.35 ± 6.10ml, p value < 0.01). Among non-DM xvii subjects a significantly negative correlation was observed between fasting GB volume and BMI (r= -0.27, p value < 0.05). Among DM patients, fasting GB volume was significantly correlated with BMI (r=0.5, p value < 0.001) and duration of DM (r = 0.704, p value < 0.001). Also, among DM patients, postprandial GB volume was significantly correlated with FBS (r= 0.25, p value < 0.05), BMI (r=0.57, p value < 0.001) and duration of DM (r = 0.75, p value < 0.001). Conclusion: Routine abdominal ultrasound should thus be recommended in the evaluation of type 2 diabetics, especially in those with long duration of illness and for early detection of gallbladder pathologies. 2024-07-01T00:00:00Z https://dspace.sduaher.ac.in/jspui/handle/123456789/9348 Title: ROLE OF SHEAR WAVE ELASTOGRAPHY OF PLACENTA IN NORMAL AND PRE-ECLAMPTIC PREGNANCIES IN THIRD TRIMESTER Authors: SHANTALA SAWKAR Abstract: INTRODUCTION Pre-eclampsia (PE) is a pregnancy-related condition characterized by new-onset hypertension (with systolic blood pressure > 140 mm Hg and diastolic blood pressure > 90 mm Hg on two occasions at least 4 hours apart, or more severe cases with higher values) along with proteinuria (elevated protein levels in urine). This condition resolves within the first 6 weeks after childbirth. This abnormal placental attachment and ineffective invasion of trophoblast cells into the muscular spiral arteries leads to hypoxia and placental ischemia. Shear wave elastography (SWE) is an innovative ultrasound technique designed to assess the elasticity of soft tissues. In the placenta, increased stiffness is a consequence of ischemia-related processes including inflammation, necrosis, infarction and fibrosis. The present study is planned to assess the utility of SWE in evaluation of placental function and can be used as a supplement to existing methods for prediction of PE. OBJECTIVES  To assess placental stiffness by shear wave elastography in third trimester.  To compare placental elastography findings in normal and pre- eclamptic pregnancies in third trimester. xviii MATERIAL AND METHODS This prospective case control study which includes 134 pregnant women in third trimester referred for obstetric scan on whom B-mode sonography and shear wave elastography was performed. Obstetric sonography and elastography of placenta will be performed using Philips EPIQ5 system equipped with shear wave point quantification, ELASTPQ, using curvilinear broadband transducer C5-1MHz. 67 women who had clinically normal pregnancies with normal fetal biometric measurements without any perinatal complications formed group A, and 67 women who had a clinical diagnosed preeclampsia formed group B. RESULTS Shear wave elastography values for case group 10.98 (9.70-13.13) were significantly higher than those for control group 2.90 (2.78-3.58) (P<0.001). No statistically significant difference was found between the elasticity values measured at the centre or edge of the placenta. CONCLUSION This study demonstrates that the use of shear wave elastography for detecting Placental stiffness has a good diagnostic performance for detecting Pre-Eclampsia. Shear wave elastography is a novel technique for characterizing tissues that is helpful for assessing tissue characterization, placental function and serves as an addition to current preeclampsia prediction tools. 2024-07-01T00:00:00Z https://dspace.sduaher.ac.in/jspui/handle/123456789/9347 Title: ROLE OF SHEAR WAVE ELASTOGRAPHY IN ASSESSING ACHILLES TENDON IN NORMAL INDIVIDUALS, DIABETIC PATIENTS WITH AND WITHOUT FOOT COMPLICATIONS Authors: RISHI PRAJWAL, H L Abstract: Introduction: Diabetes mellitus (DM) is an endocrine disorder which is characterized by several metabolic abnormalities as well as long-term complications. Among the dreaded consequences of diabetes mellitus (DM) is diabetic foot. According to a number of studies, diabetic patients may experience foot issues as a result of alterations in the Achilles tendon (AT). In diabetic patients, early detection of these changes may prevent impending foot complications. Aim:  To perform ultrasound and document the thickness of the Achilles tendon in normal individuals, diabetic patients with and without foot complications.  To assess the role of shear wave elastography in assessing Achilles tendon stiffness and deriving cut-off values in normal individuals, diabetic patients with and without foot complications. Methods: Shear wave elastography (SWE) was used to assess the elasticity of AT in 55 healthy volunteers, 55 patients with type 2 DM (T2DM) without foot complications and 55 patients with type 2 DM with foot complications. The thickest part of the middle portion of the Achilles tendon, which is nearly 2-6 cm proximal to the calcaneus insertion, was chosen for shear wave elastographic examinations & thickness calculation. Results: The study found a male predominance with 121 (73.3%) males and 44 (26.7% females) patients. The mean age was 55.14±10.11, with no significant differences in age or disease conditions. Diabetic patients had significantly higher fasting blood sugar (FBS) levels and post-prandial blood sugar (PPBS) levels compared to healthy individuals. The AT thickness was more in diabetic patients with foot complications compared to non-diabetic controls and diabetic patients without foot complications. The cutoff value for AT thickness xvi for healthy vs T2DM without foot complications was 7.55mm, with 96.4% sensitivity and 79.4% specificity. The cutoff value for AT thickness for T2DM without vs with foot complications was 8.95mm, with 81.8% sensitivity and 78.18% specificity. The Young's modulus was significantly lower in diabetic patients with foot complications as compared to the other two groups, which implies that the elasticity of AT in patients with foot complications was significantly lower as compared to those diabetic patients without foot complications. A cut-off value of 120 kPa had a very good diagnostic accuracy (AUC = 0.879) to differentiate between the AT stiffness of diabetic patients with foot complications and diabetic patients without foot complications with a specificity of 78.18% and sensitivity of 81.5 %.. Conclusion: Modifications in the structure of AT occurs before the onset of foot complications in diabetic patients. Reduced elasticity & thickening of AT is a reliable marker of impending foot complications in diabetic patients 2024-07-01T00:00:00Z