https://dspace.sduaher.ac.in/jspui/handle/123456789/764 2026-02-03T03:25:18Z https://dspace.sduaher.ac.in/jspui/handle/123456789/9576 Title: A new horizon in the prescription pattern of drugs for osteoarthritis in a tertiary care hospital: A prospective observational study Authors: Suneetha, Raghu; Raghu Murthy, N Abstract: Background: Osteoarthritis (OA) is a significant contributor to chronic pain, mainly affecting lower extremity joints like the knee and hip, and causing considerable impairment in elderly individuals. OA treatment focuses on easing discomfort and enhancing mobility. Despite their adverse unfavorable effects, non-steroidal anti-inflammatory medications (NSAIDs) are frequently used for symptom alleviation. However, there is still a need for secure and efficient alternative therapies that could provide OA patients with both symptomatic relief and disease-modifying benefits. Despite the indisputable fact that the disease has a substantial socioeconomic impact on patients, there is not much research available to reflect on the medicine prescription pattern in OA. Aim and Objectives: The objectives of this study were to assess the prescription pattern and their rationality in patients with OA in a tertiary care hospital. Materials and Methods: A cross-sectional, prospective, and observational study conducted in the orthopedics department for all newly diagnosed and old treated patients with OA. Around 350 patients were taken into the study and their prescriptions were scrutinized. Descriptive statistics were used to analyze the data and present it as percentages. Results: Over 61.7% of females were affected compared to 38.3% of males with OA. The knee joint (76.2%) followed by the hip joint (13.7%) were the most common joints involved. Aceclofenac and diclofenac were the most common NSAIDs used in the patients, whereas piroxicam was the least prescribed drug. Gastroprotective agents, calcium supplements, and SYSDOA were the commonest adjuvants used in the treatment of OA patients. Conclusions: Even though NSAIDs are favored, SYSDOA and non-pharmacological treatments such as lifestyle changes, and frequent mild exercise have changed the treatment plan for OA. 2023-01-01T00:00:00Z https://dspace.sduaher.ac.in/jspui/handle/123456789/9503 Title: Fall‑Related Injuries and Their Prevention Strategies of In‑Patient Population in Tertiary Health Care Setup Authors: Suneetha, Raghu; Raghu, MN; Amitha, P Marla; Supala, S Kotian; Nirmala Kumari Abstract: Introduction: In‑hospital falls are one of the major causes of morbidity and rarely mortality in India. Most horrible part is most of the times these are considered as “never happened events” and they are never recorded and recognised. Till now, there are only few documented studies, especially in the Indian setup regarding the study of fall‑related injuries in hospital. Aim: The main aim of this study is the documentation and interpretation of context and characteristics of fall and fall‑related injuries. Using internal communication system, in‑built software, falls and fall‑related injuries were documented. An extensive search was made to find out time and cause for the fall‑ and fall‑related injuries. Many inbuilt programs were made to prevent and reduce fall‑ and fall‑related injuries. Results: Most of falls and fall‑related injuries occurred during the night and early morning times in wash rooms and toilets. Elderly people (60–89 years) and males had more incidence of falls compared to other age groups and females respectively. Conclusion: Falls and fall‑related injuries in hospital can lead to significant secondary complications for individual patients. Since they are easily preventable, they represent an attractive target to increase the quality of care and lower the cost of overall medical treatment. 2022-10-01T00:00:00Z https://dspace.sduaher.ac.in/jspui/handle/123456789/9262 Title: A Study of Lifestyle Modifications With and Without Metformin in Prediabetic Subjects Authors: Asha, Basavareddy; Narayana, Sarala; Venkatarathnamma, P. Nanjappa; Sumathi, M. Eshwarappa Abstract: Purpose: Prediabetes is a stage in the natural history of impaired glucose metabolism rather than as a distinctive clinical entity. The primary objective was to compare the effect of lifestyle modifications (LSMs) with and without metformin in prolonging the onset of diabetes mellitus in prediabetics. Materials and Methods: This study is an open label, parallel group comparative study conducted from 2016 to 2020. One hundred and four prediabetic subjects were assigned to two groups: group I (51) LSM and group II (53) metformin 500 mg along with LSM. Baseline investigations included fasting blood sugar (FBS), post‑prandial blood sugar (PPBS), HbA1c, and lipid profile, followed up for 12 months. Results: The baseline parameters were comparable between the groups. In both the groups, there was a significant reduction in abdominal circumference, total cholesterol, triglycerides, low‑density lipoprotein, FBS, PPBS, and HbA1c between baseline and 1 year. There was no significant difference between groups I and II in reduction of all the above‑mentioned parameters. The outcomes of prediabetic subjects after 1 year of treatment in both the groups were comparable. Only one (2.1%) subject had more than 126 mmHg FBS in the LSM group. The adverse effects observed were dizziness, nausea, flatulence, myalgia, abdominal pain, and heart burn, which were mild to moderate in intensity and in most patients it subsided with time. Conclusion: LSM alone was equivalent to LSM along with metformin in effective control of blood sugars. Lipid profile and weight may be significantly reduced. 2022-09-01T00:00:00Z https://dspace.sduaher.ac.in/jspui/handle/123456789/8444 Title: Corona Virus Infection (Novel CoVid 19) - Update on specific and supportive medications Authors: Asha B Abstract: Coronavirus belongs to the family of Coronaviridae and is structurally enveloped with positive sense single strand. The virus undergoes replication by transcription of a minus strand template by RNA dependent RNA polymerase. The search is ongoing for the specific targeted treatment of corona virus infection. Among the available drugs to treat viral infections, there are few with promise to treat or reduce viral load. Never the less prevention is the best method to tackle the viral infection. The drugs used in the treatment of CoVid 19 according to the evidence available from the past with management of Severe Acute Respiratory Syndrome Corona Virus (SARS Covid 2) and Middle East Respiratory Syndrome Corona Virus (MERS Covid). The options available for treatment of Covid 19 are antiviral drugs and supportive interventions. The currently available drugs used in viral infections are explored for their additional benefit in treating CoVid 19 along with the immune boosters which include vitamins, essential minerals and biological response modifiers. 2020-01-01T00:00:00Z