https://dspace.sduaher.ac.in/jspui/handle/123456789/770 Sun, 08 Feb 2026 21:56:32 GMT 2026-02-08T21:56:32Z https://dspace.sduaher.ac.in/jspui/handle/123456789/9637 Title: Comparison of Kampala Trauma Score and Trauma Injury Severity Score in Predicting Mortality in Trauma Patients Authors: Chalana, N R.; Prakash, Dave.; Sreeramulu, P N.; Krishna Prasad., K; Shashirekha, C A Abstract: Introduction: Trauma is one of the leading causes of mortality and morbidity worldwide. The mechanism of trauma is classified as either blunt or penetrating. Blunt trauma is due to motor vehicle-related injuries, falls, and assaults, whereas firearms and stabbings account for most penetrating injuries. Fifty percent of deaths occur within minutes of injury, resulting from massive bleeding or severe neurologic damage. This study aims to assess the Kampala Trauma Score and Trauma Injury Severity Score system with the outcome, i.e., mortality. Methods: It is a prospective descriptive cohort study. A total of 285 patients were involved in the study. All patients suspected of having trauma were scored using TRISS and KAMPALA SCORES at arrival time. Clinical assessment, relevant blood investigations, and radiological investigations were done in the emergency department at the time of presentation in a tertiary care teaching hospital and repeated after 24 hours. The follow-up for mortality till the 30th post-trauma day was recorded. Physiological parameters at the time of initial assessment were recorded, including Systolic Blood Pressure (SBP), Glasgow Coma Scale (GCS) score, respiratory rate (RR), heart rate (HR), and oxygen saturation2. Chest X-ray, CT scan, USG abdomen and pelvis, and blood investigation were done when indicated. Results: Of the 285 patients eligible for the study, mortality was 21(13.57%). The area under the curve for TRISS and KTS were 0.951 and 0.980, respectively, at the time of admission and 0.955 and 0.989 after 24 hours. The diagnostic accuracy of KTS was higher than the TRISS, indicating that KTS was better at predicting mortality in trauma patients than the complex TRISS. Conclusion: The Kampala Trauma Scoring System is better at predicting mortality than the Trauma Injury Severity Scoring System in trauma patients. It predicted early and late mortality better with better diagnostic accuracy than the TRISS. Sun, 01 Jan 2023 00:00:00 GMT https://dspace.sduaher.ac.in/jspui/handle/123456789/9637 2023-01-01T00:00:00Z https://dspace.sduaher.ac.in/jspui/handle/123456789/9561 Title: A Case Report of Klippel-Feil Syndrome Presenting as Tetraplegia Authors: Bhavana Chowdary, Madineni.; Manohar, S.; Dinesh Kumar.; Athish, K K Abstract: Cervical spine assessment is an important step in patients who sustained trauma. Klippel-Feil syndrome (KFS) is a complex syndrome with an abnormal fusion of cervical vertebrae at C2 and C3, which is caused by a failure in the division or normal segmentation of the cervical spine vertebrae in early fetal development. This condition leads to a characteristic appearance of a short neck, low hairline, facial asymmetry, and limited neck mobility. People with congenital defects like KFS are more prone to cervical spine injury. KFS is a relatively rare disease. Trivial trauma can lead to neurologic symptoms in such individuals. We present a 32-year-old male, with an alleged history of falls from height with traumatic injury to his head and spine. Following the event, he was unable to move all four limbs. The patient’s short neck was noted. Magnetic resonance imaging (MRI) of the spine revealed multilevel fusion of four cervical vertebrae (C3-C7) with a single fused spine which is highly uncommon. Myelopathy secondary to C3-C4 disk protrusion is also seen. The patient was diagnosed with KFS and managed conservatively. The abnormal fusion in KFS predisposes to neurologic injury owing to altered biomechanics of the spine leading to hypermobility of the adjacent normal spine, spondylolisthesis, and stenosis, thereby increasing the likelihood of injuries. Screening and identification of KFS in young children are essential as counseling for lesser strenuous activity might avoid neurological injury and promote better neurological outcomes in the future. Thu, 01 Jun 2023 00:00:00 GMT https://dspace.sduaher.ac.in/jspui/handle/123456789/9561 2023-06-01T00:00:00Z https://dspace.sduaher.ac.in/jspui/handle/123456789/9551 Title: Correlation of prognostic factors of carcinoma breast with Ki 67 proliferation assay Authors: Rohit Kumar, Yadamreddy; Sreeramulu, P N; Hemalata, A; Manjunath, G N; Srinivasa, D Abstract: Abstract---Prognostic factors are important for the diagnosis of breast cancer as it helps in identification of high risk patients. The objective of the study is to assess the proliferation index, Ki-67 and correlate it with other markers. The present study was a cohort study conducted in the Department of General Surgery at Tertiary Care Teaching Hospital over a period of 1 year with a sample size of 98. All the patients meeting the inclusion and exclusion criteria are recruited sequentially by convenient sampling until the sample size is attained, with the agreement of the institutional ethics committee. A total of 98 patients with a mean age of 53.61 ± 12.48 years were studied in the final analysis. The mean duration of lump was 4.62 ± 2.18 months and only 6.12% had the complaint of pain. Majority of them had stage IIIB carcinoma at 43.88%, followed by stage IIA at 27.55%, 15.31% stage IIB, 13.27% stage IIIA. At cut off 20, 69(70.40%) had ki67 SUROLIHUDWLRQ LQGH[ DQG KDG &RUUHODWLRQ RI .L-67 Index with expression of estrogen receptor status had a p value of 0.019 and with progesterone receptor status, p 0.003 which was significant. In the age group of 31 to 60 years, majority of them had .L-67 but age showed no significant association with Ki-67. Duration of lump, menstrual history, physical characteristics of the effected breast, physical characteristics of the lump, size of the lump, stage and lymph node status had no significant association with the 3 3 1 6 Ki-67 expression. While the estrogen receptor expression had significant association with Ki-67 with p value 0.019, the expression of progesterone receptor showed a significant correlation with Ki-67 with p 0.003. Fri, 01 Apr 2022 00:00:00 GMT https://dspace.sduaher.ac.in/jspui/handle/123456789/9551 2022-04-01T00:00:00Z https://dspace.sduaher.ac.in/jspui/handle/123456789/9540 Title: Correlation of prognostic factors of carcinoma breast with Ki 67 proliferation assay Authors: Yadamreddy, Rohit Kumar; Sreeramulu, P N; Hemalata, A; Manjunath, G N; Srinivasa, D Abstract: Prognostic factors are important for the diagnosis of breast cancer as it helps in identification of high risk patients. The objective of the study is to assess the proliferation index, Ki-67 and correlate it with other markers. The present study was a cohort study conducted in the Department of General Surgery at Tertiary Care Teaching Hospital over a period of 1 year with a sample size of 98. All the patients meeting the inclusion and exclusion criteria are recruited sequentially by convenient sampling until the sample size is attained, with the agreement of the institutional ethics committee. A total of 98 patients with a mean age of 53.61 ± 12.48 years were studied in the final analysis. The mean duration of lump was 4.62 ± 2.18 months and only 6.12% had the complaint of pain. Majority of them had stage IIIB carcinoma at 43.88%, followed by stage IIA at 27.55%, 15.31% stage IIB, 13.27% stage IIIA. At cut off 20, 69(70.40%) had ki67 SUROLIHUDWLRQ LQGH[ DQG KDG &RUUHODWLRQ RI .L-67 Index with expression of estrogen receptor status had a p value of 0.019 and with progesterone receptor status, p 0.003 which was significant. In the age group of 31 to 60 years, majority of them had .L-67 but age showed no significant association with Ki-67. Duration of lump, menstrual history, physical characteristics of the effected breast, physical characteristics of the lump, size of the lump, stage and lymph node status had no significant association with the Ki-67 expression. While the estrogen receptor expression had significant association with Ki-67 with p value 0.019, the expression of progesterone receptor showed a significant correlation with Ki-67 with p 0.003.` Fri, 01 Apr 2022 00:00:00 GMT https://dspace.sduaher.ac.in/jspui/handle/123456789/9540 2022-04-01T00:00:00Z