Morphological and Immunohistochemical Categorization of Malignant Lymphomas

Abstract

Lymphomas are broadly classi ed in to Hodgkins lymphoma (HL) and Non Hodgkins lymphoma. Immunohistochemistry helps in better understanding of pathogenesis and also useful in the characterization of immunophenotype in most of the malignant lymphomas. Aims & Objectives: The current study was undertaken to categorize malignant lymphomas based on morphological and immunohistochemical  ndings. Materials and Methods: Fifty cases of Lymphomas were diagnosed in the Department of Pathology, at MVJ Medical College Research Hospital, over a period of two year (between April 2015 and April 2017). The data was analyzed with respect to age, sex, histomophological and immunohistochemical characters. Results: Out of 50 cases, 12 were of HL (24%) and 38 cases (76%) were NHL. Among NHL, B-cell and T-cell lymphomas were of equal incidence. Male’s outnumbered females (68%) & maximum incidence of lymphomas including both sexes was seen in age group 51-60 years followed by age group 41–50 years. Conclusion: IHC is a useful adjunct modality with H&E stain in diagnosis and classi cation of malignant lymphomas.