Comparative Evaluation of Quality Parameters of Platelet Stored in Additive Solution versus Plasma

Abstract

extend the shelf life of platelets beyond 5 days without compromising their qualities. Materials and Methods: The study is being done to compare in vitro changes of platelet indices‑platelet count, mean platelet volume, platelet distribution width (PDW), pH and swirling in stored platelet concentrate (PC) with and without platelet additive solution (PAS) for 0,3,5,7 and 10 days. Results: Serial measurements of various parameters in PCs with and without PAS showed that PCs stored in PAS were better maintained and had optimal quality standards throughout the extended storage time as compared to the PCs without PAS. The results obtained in both categories were statistically significant (P < 0.001). Conclusion: Our study showed that the use of PAS in the PCs increased the shelf life and improved the viability of platelets as compared to the PCs without PAS.