A COMPARITIVE CLINICAL STUDY OF EFFECT OF INTRAVENOUS DEXMEDETOMIDINE ON INTRATHECAL LOW DOSE HYPERBARIC BUPIVACAINE V/S HYPERBARIC BUPIVACAINE WITH FENTANYL IN PATIENTS UNDERGOING INFRAUMBILICAL SURGERIES

Abstract

Background: Spinal anaesthesia has many advantages like low cost, reduced risk of aspiration even in patients who are considered to be full stomach and reduced blood loss. There is relaxation of abdominal muscles and this facilitates surgical approach. The main limitation of spinal anaesthesia is that it is limited in duration2 and patient’s anxiety which adds to the technical difficulties. OBJECTIVES: 1. To assess the Duration of onset of sensory and motor blockade and Total duration of sensory and motor blockade. 2. To find out the Changes in hemodynamic parameters; Heart rate (HR), Systolic blood pressure (SBP), Diastolic blood pressure (DBP), Mean arterial pressure (MAP) at various intervals following subarachnoid block, Sedation scores using Ramsay sedation score(RSS) and Adverse effects of drugs like excessive sedation and post-operative nausea and vomiting. MATERIAL & METHODS: Study Design: A prospective, randomized, comparative study. Study area: Department of Anaesthesia, Mysore Medical College, Karnataka. Study Period: 1 year. Study population: Adult patients of either sex, aged between 18-55 years belonging to ASA class I and II without any severe co morbid diseases scheduled for elective infra umbilical surgeries. Sample size: study consisted a total of 80 cases. Study tools and Data collection procedure: The data was collected in a pretested proforma, after obtaining clearance from the institutional ethical and scientific committee and informed written consent from the patients, 80 ASA class I and II patients posted for elective infra umbilical surgeries were selected. They were randomly divided using shuffled opaque envelope technique into 2 groups of 40 patients each.